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RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma

RRM2 silencing suppresses malignant phenotype and enhances radiosensitivity via activating cGAS/STING signaling pathway in lung adenocarcinoma

Posted on May 12, 2021April 23, 2021 by Antonio

As one of the widespread malignancy, lung adenocarcinoma (LUAD) is characterised by low 5-year survival price. This analysis aimed to analyze the results of ribonucleotide reductase regulatory subunit M2 (RRM2) on malignant organic behaviors and activation of cGAS/STING pathway. We additionally explored the synergistic sensitization mechanisms of RRM2 and radiotherapy. Bioinformatic instruments have been used… Continue reading

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