Ferumoxytol is the one USPIO clinically out there within the U.S. and is a negatively charged USPIO that has potential use for monitoring and characterization of macrophage-infiltrated cardiovascular buildings. As an iron complement that’s authorized for remedy of iron deficiency anemia, the iron core of ferumoxytol is integrated into the physique as soon as it’s phagocytosed by macrophages. In organs or tissues with excessive inflammatory mobile infiltration, resembling atherosclerotic plaques and myocardial infarction, localization of iron-laden macrophages might be visualized on delayed MRI.
The iron core of ferumoxytol alters the magnetic susceptibility and ends in shortening of T2* and T2 rest charges. Areas with excessive focus seem hypointense (destructive distinction) on T2 and T2* MRI. Lately, in vitro findings assist the potential specificity of ferumoxytol interactions with macrophage subtypes, which has implications for therapeutic interventions. With rising issues about gadolinium retention within the mind and different tissues, the worth of ferumoxytol-enhanced MR for focused scientific imaging is aided by its constructive security profile in sufferers with impaired renal perform.
Unsupervised Okay-means evaluation, through the hole statistics, in addition to hierarchical clustering evaluation revealed three essential clusters with distinct reactivity intensities and patterns. These patterns weren’t recapitulated by adjusting the VITROS CoV2T or RVPNT assay thresholds. Plasma categorized by COVAM reactivity patterns affords potential to enhance CCP therapeutic efficacy CoV2T alone. Using a SARS-CoV-2 antigen array can qualify CCP for administration as a remedy for acute COVID-19, and interrogate vaccine immunogenicity and efficiency in preclinical, scientific research, and routine vaccination to establish antibody responses predictive of safety from an infection and illness.
OIP5-AS1 was elevated in trastuzumab-resistant breast most cancers cells, and OIP5-AS1 knockdown rescued trastuzumab sensitivity. Extracellular OIP5-AS1 was packaged into exosomes, which had been secreted by trastuzumab-resistant cells, and could possibly be absorbed by trastuzumab-sensitive cells in breast most cancers. Importantly, intercellular switch of OIP5-AS1 through exosomes enhanced trastuzumab resistance in vitro. OIP5-AS1 was a sponge of miR-381-3p; moreover, miR-381-3p focused HMGB3. Murine xenograft evaluation confirmed exosomal OIP5-AS1 induced trastuzumab resistance in vivo. Exosomal OIP5-AS1 was dysregulated within the serum of breast most cancers sufferers and could be a promising diagnostic biomarker in trastuzumab resistance.
New diagnostic molecular markers and biomarkers in odontogenic tumors
Odontogenic tumors comprised of advanced heterogeneous lesions that numerous from harmatomas to malignant tumors with totally different conduct and histology. The etiology of odontogenic tumors shouldn’t be precisely decided and pathologists cope with challenges in prognosis of odontogenic tumors as a result of they’re uncommon and obtained experiences are troublesome to judge. On this examine, we describe immunohistochemical and molecular markers in prognosis of odontogenic tumors moreover superior diagnostic method. Immunohistochemical options of odontogenic tumors beside the scientific options and radiological discovering can assist us to find out the proper prognosis.
Though these markers are neither particular nor delicate sufficient, however evaluation of gene expression offers definitive affirmation of prognosis. As well as, “-omics” expertise detected particular molecular alternation related to etiology resembling genomics, epigenomics, transcriptomics, proteomics and metabolomics. The put up transcriptional occasions resembling DNA methylation and chromatin reworking by histone modification have an effect on the adjustments in epigenome. Moreover, non-coding RNAs like micro-RNAs, lengthy noncoding RNA (lncRNA) and small non-coding RNA (snoRNA) play regulatory position and influence odontogenesis.
Molecular marker suggest their potential position in etiopathogenesis of odontogenic tumors and appropriate candidate in diagnostic, prognostic and therapeutic approaches along with affected person administration. For future evaluations, organoid represents in vitro tumor model-study for tumor conduct, metastasis and invasion, drug screening, immunotherapy, scientific trial, hallmarks affiliation with prognosis and evolution of personalised anti-cancer remedy. Furthermore, organoid biobank assist us to examine genetic profile. We predict extra investigation and research are wanted to achieve these knowledges that may shift therapeutic approaches to focus on remedy.
DCUN1D1 promotes tumour progress in prostate most cancers and its impact on DU145 in vitro
To match the expression ranges of Faulty In Cullin Neddylation 1 Area Containing 1 oncogene in prostate most cancers tissues and regular prostate tissues, to discover its impact on cancerous cells, and to research its underlying mechanisms on such cells in vitro.The cross-sectional examine was carried out at Guangdong Key Laboratory of Medical Molecular Drugs and Diagnostics from Jan 03,2017 to Nov 05,2018, and comprised prostate tissue samples on which immunohistochemistry was used to detect the expression of Faulty In Cullin Neddylation 1 Area Containing 1 oncogene.
Brief hairpin ribonucleic acid expression plasmid focusing on the oncogene was constructed and transferred into prostate cance cell line DU145. The roles of the oncogene in prostate most cancers development had been confirmed in vitro. The expression of vimentin and epithelial cadherin influenced by the oncogene had been detected utilizing Western blot. Knowledge was analysed utilizing SPSS 24.Of the 80 samples, 3(3.75%) had been regular prostate tissues, 7(8.75%) adjoining regular prostate tissues, 20(25%) hyperplasia, and 50(62.5%) prostate most cancers tissues.
 Protease Activity Assay Kit |
|
AR4011-unit |
BosterBio |
unit |
EUR 408 |
 Mitochondria Activity Assay Kit |
|
KC310100 |
Biochain |
1 kit |
EUR 417 |
 DAG Kinase Activity Assay Kit |
|
MET-5036 |
Cell Biolabs |
50 assays |
EUR 540 |
 MAT Activity Assay |
|
IK00401 |
Arthus |
96 tests |
EUR 1012.8 |
|
Description: Methionine Adenosyltransferase (MAT) activity assay kit |
 Caspase-1 Activity Assay Kit |
|
AR4003-100Assays |
BosterBio |
100 Assays |
EUR 616.8 |
Caspase-1 Activity Assay Kit |
|
AR4003-25Assays |
BosterBio |
25 Assays |
EUR 283.2 |
Caspase-1 Activity Assay Kit |
|
AR4003-50Assays |
BosterBio |
50 Assays |
EUR 408 |
 Caspase-2 Activity Assay Kit |
|
AR4004-100Assays |
BosterBio |
100 Assays |
EUR 616.8 |
Caspase-2 Activity Assay Kit |
|
AR4004-25Assays |
BosterBio |
25 Assays |
EUR 283.2 |
Caspase-2 Activity Assay Kit |
|
AR4004-50Assays |
BosterBio |
50 Assays |
EUR 408 |
 Activity Assay Kit) Hexokinase (HK) Activity Assay Kit |
|
MET-5087 |
Cell Biolabs |
100 assays |
EUR 609.6 |
 Beta Secretase Activity Assay Kit |
|
55R-1383 |
Fitzgerald |
100 assays |
EUR 1002 |
|
Description: Assay Kit for detection of Beta Secretase Activity in the research laboratory |
 KinaseSTAR Akt Activity Assay Kit |
|
K2080-40 |
ApexBio |
40 assays |
EUR 885.6 |
 Akt Activity Assay Kit, KinaseSTAR |
|
K435-40 |
Biovision |
each |
EUR 816 |
 OxiSelect ORAC Activity Assay Kit |
|
STA-345 |
Cell Biolabs |
192 assays |
EUR 692.4 |
|
Description: The ORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect ORAC Activity Assay measures this capacity in less than 2 hours from a wide variety of sample types. |
OxiSelect ORAC Activity Assay Kit |
|
STA-345-5 |
Cell Biolabs |
5 x 192 assays |
EUR 2732.4 |
|
Description: The ORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect ORAC Activity Assay measures this capacity in less than 2 hours from a wide variety of sample types. |
 OxiSelect HORAC Activity Assay Kit |
|
STA-346 |
Cell Biolabs |
192 assays |
EUR 692.4 |
|
Description: The HORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect HORAC Activity Assay measures the degradation of free hydroxyl radicals in less than 2 hours from a wide variety of sample types. |
OxiSelect HORAC Activity Assay Kit |
|
STA-346-5 |
Cell Biolabs |
5 x 192 assays |
EUR 2732.4 |
|
Description: The HORAC assay is a powerful tool to measure the antioxidant capacity of biomolecules. Our OxiSelect HORAC Activity Assay measures the degradation of free hydroxyl radicals in less than 2 hours from a wide variety of sample types. |
 GST Colorimetric Activity Assay Kit |
|
55R-1353 |
Fitzgerald |
100 assays |
EUR 847.2 |
|
Description: Assay Kit for detection of GST activity in the research laboratory |
 Acid Phosphatase Activity Assay Kit |
|
55R-1405 |
Fitzgerald |
500 assays |
EUR 525.6 |
|
Description: Assay Kit for detection of Acid Phosphatase in the research laboratory |
Acid Phosphatase Activity Assay Kit |
|
55R-1866 |
Fitzgerald |
500 assays |
EUR 580.8 |
|
Description: Assay Kit for detection of Acid Phosphatase in the research laboratory |
 GST Colorimetric Activity Assay Kit |
|
K263-100 |
Biovision |
each |
EUR 588 |
 GST Fluorometric Activity Assay Kit |
|
K260-100 |
Biovision |
each |
EUR 561.6 |
GST Fluorometric Activity Assay Kit |
|
K2105-100 |
ApexBio |
100 assays |
EUR 602.4 |
GST Colorimetric Activity Assay Kit |
|
K2108-100 |
ApexBio |
100 assays |
EUR 634.8 |
) HDAC6 Activity Assay Kit (Fluorometric) |
|
K466-100 |
Biovision |
each |
EUR 757.2 |
 Beta Hexosaminidase Activity Assay Kit |
|
MET-5095 |
Cell Biolabs |
100 assays |
EUR 609.6 |
) Urease Activity Assay Kit (Colorimetric) |
|
K378-100 |
Biovision |
each |
EUR 601.2 |
) ATPase Activity Assay Kit (Colorimetric) |
|
K417-100 |
Biovision |
each |
EUR 516 |
 96-Well ROCK Activity Assay Kit |
|
STA-416 |
Cell Biolabs |
96 assays |
EUR 1027.2 |
|
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1. |
96-Well ROCK Activity Assay Kit |
|
STA-416-5 |
Cell Biolabs |
5 x 96 assays |
EUR 4228.8 |
|
Description: Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1. |
 Alkaline Phosphatase Activity Assay Kit |
|
55R-1402 |
Fitzgerald |
500 assays |
EUR 888 |
|
Description: Assay Kit for detection of Alkaline Phosphatase in the research laboratory |
Alkaline Phosphatase Activity Assay Kit |
|
55R-1406 |
Fitzgerald |
500 assays |
EUR 525.6 |
|
Description: Assay Kit for detection of Alkaline Phosphatase in the research laboratory |
) Uricase Activity Assay Kit (Fluorometric) |
|
K734-100 |
Biovision |
each |
EUR 614.4 |
) Plasmin Activity Assay Kit (Colorimetric) |
|
K945-100 |
Biovision |
each |
EUR 535.2 |
) Plasmin Activity Assay Kit (Fluorometric) |
|
K381-100 |
Biovision |
each |
EUR 548.4 |
) Sirtuin Activity Assay Kit (Fluorometric) |
|
K324-100 |
Biovision |
each |
EUR 686.4 |
 MAT Activity Assay 3 |
|
IK00403 |
Arthus |
48 tests |
EUR 603.6 |
|
Description: Methionine Adenosyltransferase (MAT) activity assay kit |
) Lysozyme Activity Assay Kit (Fluorometric) |
|
K236-100 |
Biovision |
each |
EUR 588 |
) Sulfatase Activity Assay Kit (Colorimetric) |
|
K675-100 |
Biovision |
each |
EUR 783.6 |
) ?-Xylosidase Activity Assay Kit (Fluorometric) |
|
K981-100 |
Biovision |
each |
EUR 705.6 |
) Neprilysin Activity Assay Kit (Fluorometric) |
|
K487-100 |
Biovision |
each |
EUR 732 |
 Lysosomal Intracellular Activity Assay Kit |
|
K448-50 |
Biovision |
each |
EUR 652.8 |
) Tyrosinase Activity Assay Kit (Colorimetric) |
|
K742-100 |
Biovision |
each |
EUR 698.4 |
 PDE4B Cell-Based Activity Assay Kit |
|
79526 |
BPS Bioscience |
500 rxns. |
EUR 610 |
|
Description: Phosphodiesterases (PDEs) play an important role in the dynamic regulation of cAMP and cGMP signaling. PDE4B has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP. Inhibition of PDE4B activity by its inhibitors leads to an elevated intracellular level of cAMP. The PDE4B gene encodes at least 4 different isoforms, and has been linked to inflammation in monocytes by its regulation of the toll-receptor pathway. It is also highly expressed in the central nervous system, and has been targeted as a potential treatment for autism, depression, schizophrenia, and other conditions._x000D_The PDE4B cell-based activity assay kit is designed for screening inhibitors of PDE4B1 in cultured cells. The assay is based on transfecting cells with the CRE luciferase reporter. CRE reporter contains the firefly luciferase gene under the control of cAMP response element (CRE). Elevation of intracellular cAMP activates CRE binding protein (CREB) to bind CRE and induce the expression of luciferase. Forskolin is commonly used to raise the intracellular level of cAMP in cell physiology studies. When cells transiently transfected with CRE reporter are activated by forskolin, the intracellular level of cAMP is upregulated, which induces the expression of CRE luciferase reporter. However, when cells are co-transfected with PDE4B1 expression vector and CRE reporter, the level of forskolin-induced cAMP is reduced, resulting in lower expression level of luciferase. When cells are treated with PDE4B inhibitor to inhibit PDE4B1 activity, cAMP level is restored, resulting in higher luciferase activity._x000D_The kit includes CRE luciferase reporter (premixed with constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency), PDE4B1 expression vector, and forskolin. |
 PDE4D Cell-Based Activity Assay Kit |
|
60505 |
BPS Bioscience |
500 rxns. |
EUR 645 |
|
Description: The PDE4D cell-based activity assay is designed for screening inhibitors of PDE4D7 in cultured cells. The assay is based on transfecting cells with the CRE luciferase reporter. _x000D_CRE reporter contains the firefly luciferase gene under the control of cAMP response element (CRE). Elevation of intracellular cAMP activates CRE binding protein (CREB) to bind CRE and induce the expression of luciferase. When cells transiently transfected with CRE reporter are activated by forskolin, the intracellular level of cAMP is upregulated, which induces the expression of CRE luciferase reporter. However, when cells are co-transfected with PDE4D7 expression vector and CRE reporter, the level of forskolin-induced cAMP is reduced, resulting in lower expression level of luciferase. When cells are treated with PDE4D inhibitor to inhibit PDE4D7 activity, cAMP level is restored, resulting in higher luciferase activity. |
) Lipoxygenase Activity Assay Kit (Fluorometric) |
|
K978-100 |
Biovision |
each |
EUR 783.6 |
) Chymotrypsin Activity Assay Kit (Fluorometric) |
|
K352-100 |
Biovision |
each |
EUR 588 |
 Acetylcholinesterase Activity Assay Kit - 100 Assays |
|
AR4001-unit |
BosterBio |
unit |
EUR 380.4 |
) ?-Glucuronidase Activity Assay Kit (Fluorometric) |
|
K514-100 |
Biovision |
each |
EUR 744 |
) Cholinesterase Activity Assay Kit (Colorimetric) |
|
K975-100 |
Biovision |
each |
EUR 770.4 |
) Deubiquitinase Activity Assay Kit (Fluorometric) |
|
K485-100 |
Biovision |
each |
EUR 639.6 |
) DNAse I Activity Assay Kit (Fluorometric) |
|
K429-100 |
Biovision |
each |
EUR 836.4 |
) Chitotriosidase Activity Assay Kit (Fluorometric) |
|
K512-100 |
Biovision |
each |
EUR 744 |
 HAT Activity Colorimetric Assay Kit |
|
K2033-100 |
ApexBio |
100 assays |
EUR 668.4 |
 HAT Activity Fluorometric Assay Kit |
|
K2034-100 |
ApexBio |
100 assays |
EUR 668.4 |
 HAT Activity Colorimetric Assay Kit |
|
K332-100 |
Biovision |
each |
EUR 646.8 |
 HAT Activity Fluorometric Assay Kit |
|
K334-100 |
Biovision |
each |
EUR 646.8 |
) Transglutaminase Activity Assay Kit (Colorimetric) |
|
K571-100 |
Biovision |
each |
EUR 861.6 |
) Factor XIa Activity Assay Kit (Colorimetric) |
|
K973-100 |
Biovision |
each |
EUR 738 |
) Factor IXa Activity Assay Kit (Fluorometric) |
|
K364-100 |
Biovision |
each |
EUR 588 |
 DPP4 Activity Fluorometric Assay Kit |
|
K779-100 |
Biovision |
each |
EUR 652.8 |
 HDAC Activity Fluorometric Assay Kit |
|
K2031-100 |
ApexBio |
100 assays |
EUR 602.4 |
 HDAC Activity Colorimetric Assay Kit |
|
K2032-100 |
ApexBio |
100 assays |
EUR 602.4 |
 PLTP Activity Fluorometric Assay Kit |
|
K2087-100 |
ApexBio |
100 assays |
EUR 802.8 |
 CETP Activity Fluorometric Assay Kit |
|
K2089-100 |
ApexBio |
100 assays |
EUR 870 |
DPP4 Activity Fluorometric Assay Kit |
|
K2178-100 |
ApexBio |
100 assays |
EUR 668.4 |
HDAC Activity Colorimetric Assay Kit |
|
K331-100 |
Biovision |
each |
EUR 588 |
HDAC Activity Fluorometric Assay Kit |
|
K330-100 |
Biovision |
each |
EUR 588 |
) Methyltransferase Activity Assay Kit (Colorimetric) |
|
K986-100 |
Biovision |
each |
EUR 777.6 |
) Methyltransferase Activity Assay Kit (Fluorometric) |
|
K521-100 |
Biovision |
each |
EUR 679.2 |
 p53 Transcription Factor Activity Assay Kit |
|
K923-100 |
Biovision |
each |
EUR 639.6 |
) Factor XIIa Activity Assay Kit (Colorimetric) |
|
K994-100 |
Biovision |
each |
EUR 751.2 |
 Activity Assay Kit) Superoxide Dismutase (SOD) Activity Assay Kit |
|
K2035-100 |
ApexBio |
100 assays |
EUR 518.4 |
) Caspase-3 Activity Assay Kit (Luminometric) |
|
K186-100 |
Biovision |
each |
Ask for price |
 Renin Activity Fluorometric Assay Kit |
|
K800-100 |
Biovision |
each |
EUR 627.6 |
 HDAC3 Activity Fluorometric Assay Kit |
|
K343-100 |
Biovision |
each |
EUR 574.8 |
 HDAC8 Activity Fluorometric Assay Kit |
|
K348-100 |
Biovision |
each |
EUR 588 |
) TEV Protease Activity Assay Kit (Fluorometric) |
|
K842-100 |
Biovision |
each |
EUR 601.2 |
 Mitochondrial Complex III Activity Assay Kit |
|
K520-100 |
Biovision |
each |
EUR 836.4 |
) Factor XIIIa Activity Assay Kit (Colorimetric) |
|
K522-100 |
Biovision |
each |
EUR 744 |
) Cathepsin E Activity Assay Kit (Fluorometric) |
|
K165-100 |
Biovision |
each |
EUR 764.4 |
 Activity Assay Kit) Lactate Dehydrogenase (LDH) Activity Assay Kit |
|
K2228-500 |
ApexBio |
500 assays |
EUR 634.8 |
) Factor VIIIa Activity Assay Kit (Fluorometric) |
|
K358-100 |
Biovision |
each |
EUR 646.8 |
 Lipase Activity Colorimetric Assay Kit |
|
K722-100 |
Biovision |
each |
EUR 614.4 |
Lipase Activity Colorimetric Assay Kit |
|
K2227-100 |
ApexBio |
100 assays |
EUR 619.2 |
) Lysyl Oxidase Activity Assay Kit (Fluorometric) |
|
K928-100 |
Biovision |
each |
EUR 639.6 |
) Glyoxalase I Activity Assay Kit (Colorimetric) |
|
K591-100 |
Biovision |
each |
EUR 588 |
 ADPsensor? Universal Kinase Activity Assay Kit |
|
K212-100 |
Biovision |
each |
EUR 698.4 |
 Trypsin Activity Colorimetric Assay Kit |
|
K771-100 |
Biovision |
each |
EUR 542.4 |
 Amylase Activity Colorimetric Assay Kit |
|
K711-100 |
Biovision |
each |
EUR 489.6 |
 Calpain Activity Fluorometric Assay Kit |
|
K2062-100 |
ApexBio |
100 assays |
EUR 752.4 |
Trypsin Activity Colorimetric Assay Kit |
|
K2176-100 |
ApexBio |
100 assays |
EUR 536.4 |
Calpain Activity Fluorometric Assay Kit |
|
K240-100 |
Biovision |
each |
EUR 705.6 |
Amylase Activity Colorimetric Assay Kit |
|
K2225-100 |
ApexBio |
100 assays |
EUR 468 |
) ?-L-Fucosidase Activity Assay Kit (Fluorometric) |
|
K542-100 |
Biovision |
each |
EUR 627.6 |
 Protease Activity Fluorometric Assay Kit |
|
K781-100 |
Biovision |
each |
EUR 464.4 |
 Fumarase Activity Colorimetric Assay Kit |
|
K596-100 |
Biovision |
each |
EUR 783.6 |
 Aldolase Activity Colorimetric Assay Kit |
|
K665-100 |
Biovision |
each |
EUR 796.8 |
 Arginase Activity Colorimetric Assay Kit |
|
K755-100 |
Biovision |
each |
EUR 646.8 |
 Thrombin Activity Fluorometric Assay Kit |
|
K373-100 |
Biovision |
each |
EUR 836.4 |
 human MMP-8 activity assay kit 96-assays |
|
QZBmmp8H |
Quickzyme |
1 plate 96 assays |
EUR 601.2 |
 human MMP-9 activity assay kit 96-assays |
|
QZBmmp9H |
Quickzyme |
1 plate 96 assays |
EUR 601.2 |
 mouse MMP-9 activity assay kit 96-assays |
|
QZBmmp9M |
Quickzyme |
1 plate 96 assays |
EUR 601.2 |
 human MMP-7 activity assay kit 96-assays |
|
QZMmmp7H |
Quickzyme |
1 plate 96 assays |
EUR 601.2 |
) 5?-Nucleotidase Activity Assay Kit (Colorimetric) |
|
K992-100 |
Biovision |
each |
EUR 796.8 |
) Oxalate Oxidase Activity Assay Kit (Fluorometric) |
|
K509-100 |
Biovision |
each |
EUR 574.8 |
) Diamine Oxidase Activity Assay Kit (Fluorometric) |
|
K496-100 |
Biovision |
each |
EUR 679.2 |
 & Activity Assay Kit) HDAC2 Immunoprecipitation (IP) & Activity Assay Kit |
|
K341-25 |
Biovision |
each |
EUR 1045.2 |
 & Activity Assay Kit) HDAC1 Immunoprecipitation (IP) & Activity Assay Kit |
|
K342-25 |
Biovision |
each |
EUR 1038 |
 & Activity Assay Kit) HDAC3 Immunoprecipitation (IP) & Activity Assay Kit |
|
K344-25 |
Biovision |
each |
EUR 901.2 |
 Activity Assay Kit (Fluorometric)) ?-Secretase (BACE1) Activity Assay Kit (Fluorometric) |
|
K388-100 |
Biovision |
each |
EUR 724.8 |
 KinaseSTAR JNK Activity Screening Kit |
|
K2078-40 |
ApexBio |
40 assays |
EUR 769.2 |
 JNK Activity Screening Kit, KinaseSTAR |
|
K430-40 |
Biovision |
each |
EUR 711.6 |
 human MMP-14 activity assay kit 96-assays |
|
QZBmmp14H |
Quickzyme |
1 plate 96 assays |
EUR 601.2 |
 Aconitase Activity Colorimetric Assay Kit |
|
K716-100 |
Biovision |
each |
EUR 601.2 |
 Invertase Activity Colorimetric Assay Kit |
|
K674-100 |
Biovision |
each |
EUR 588 |
 Urokinase Activity Fluorometric Assay Kit |
|
K728-100 |
Biovision |
each |
EUR 652.8 |
Aconitase Activity Colorimetric Assay Kit |
|
K2226-100 |
ApexBio |
100 assays |
EUR 619.2 |
 Activity Assay Kit (Fluorometric)) Aromatase (CYP19A) Activity Assay Kit (Fluorometric) |
|
K983-100 |
Biovision |
each |
EUR 744 |
) Phospholipase A2 Activity Assay Kit (Fluorometric) |
|
K400-100 |
Biovision |
each |
EUR 679.2 |
) Plasma Kallikrein Activity Assay Kit (Colorimetric) |
|
K997-100 |
Biovision |
each |
EUR 744 |
) Glucose Isomerase Activity Assay Kit (Colorimetric) |
|
K491-100 |
Biovision |
each |
EUR 588 |
) Pepsin/Pepsinogen Activity Assay Kit (Fluorometric) |
|
K446-100 |
Biovision |
each |
EUR 561.6 |
 OxiSelect Superoxide Dismutase Activity Assay Kit |
|
STA-340 |
Cell Biolabs |
100 assays |
EUR 762 |
|
Description: Superoxide dismutase (SOD), which catalyzes the dismutation of the superoxide anion into hydrogen peroxide and molecular oxygen, is one of the most important antioxidant enzymes. SOD enzymes are classified into three groups: cytosolic CuZn-SOD, mitochondrial Mn-SOD, and extracellular Ec-SOD. Our OxiSelect Superoxide Dismutase Activity Assay uses a xanthine/xanthine oxidase (XOD) system to generate superoxide anions and a chromagen to produce a water-soluble formazan dye upon reduction by superoxide anions. The superoxide dismutase activity is determined as the inhibition or reduction of chromagen. |
 Proteasome Activity Fluorometric Assay Kit |
|
K2096-100 |
ApexBio |
100 assays |
EUR 602.4 |
Proteasome Activity Fluorometric Assay Kit |
|
K245-100 |
Biovision |
each |
EUR 574.8 |
 Human tPA Chromogenic AssaySense Activity Assay Kit |
|
CT1001 |
AssayPro |
96 Well Plate |
EUR 702 |
 PicoProbe? Lactate Dehydrogenase Activity Assay Kit |
|
K730-500 |
Biovision |
each |
EUR 698.4 |
) Cytidine Deaminase Activity Assay Kit (Fluorometric) |
|
K451-100 |
Biovision |
each |
EUR 561.6 |
 Activity Assay Kit (Fluorometric)) Cyclooxygenase (COX) Activity Assay Kit (Fluorometric) |
|
K549-100 |
Biovision |
each |
EUR 502.8 |
) Beta-Mannosidase Activity Assay Kit (Fluorometric) |
|
K2045-100 |
Biovision |
100 assays |
EUR 661.2 |
 Activity Assay Kit (Colorimetric)) Gluconokinase (GntK) Activity Assay Kit (Colorimetric) |
|
K319-100 |
Biovision |
each |
EUR 874.8 |
 OxiSelect Catalase Activity Assay Kit, Fluorometric |
|
STA-339 |
Cell Biolabs |
500 assays |
EUR 908.4 |
|
Description: Catalase is a ubiquitous enzyme that destroys hydrogen peroxides formed during oxidative stress. Our OxiSelect Catalase Activity Assay Kit measures catalase activity in less than one hour from a variety of samples including blood, cells and tissues. Each kit provides sufficient reagents to perform up to 500 assays in a 96-well microtiter plate. This includes blanks, catalase standards and unknown samples. The OxiSelect Catalase Activity Assay Kit (Fluorometric) provides a 40-fold increase in sensitivity compared to our colorimetric assay. |
) OxiSelect Catalase Activity Assay Kit (Colorimetric) |
|
STA-341 |
Cell Biolabs |
96 assays |
EUR 811.2 |
|
Description: Catalase is a ubiquitous enzyme that destroys hydrogen peroxides formed during oxidative stress. Our OxiSelect Catalase Activity Assay Kits measure catalase activity in less than one hour from a variety of samples including blood, cells and tissues. Each kit provides sufficient reagents to perform up to 100 assays in a 96-well microtiter plate, or 50 assays in microcentrifuge tubes. This includes blanks, catalase standards and unknown samples. Direct spectrophotometric detection of catalase activity with ultraviolet light can cause interference from proteins and other biological components. The OxiSelect Catalase Activity Assay Kit (Colorimetric) utilizes visible light (520 nm), which reduces sample interference. The OxiSelect Catalase Activity Assay Kit (Fluorometric) provides a 40-fold increase in sensitivity compared to our colorimetric assay. |
 Activity Fluorometric Assay Kit) HAT (H4) Activity Fluorometric Assay Kit |
|
K336-100 |
Biovision |
each |
EUR 601.2 |
 Collagenase Activity Colorimetric Assay Kit |
|
K792-100 |
Biovision |
each |
EUR 489.6 |
 ?-Glucosidase Activity Colorimetric Assay Kit |
|
K690-100 |
Biovision |
each |
EUR 660 |
) PAF Acetylhydrolase Activity Assay Kit (Colorimetric) |
|
K765-100 |
Biovision |
each |
EUR 535.2 |
 Colorimetric Activity Assay Kit) Myeloperoxidase (MPO) Colorimetric Activity Assay Kit |
|
K744-100 |
Biovision |
each |
EUR 698.4 |
 Fluorometric Activity Assay Kit) Myeloperoxidase (MPO) Fluorometric Activity Assay Kit |
|
K745-100 |
Biovision |
each |
EUR 660 |
 Peroxidation Activity Assay Kit) Myeloperoxidase (MPO) Peroxidation Activity Assay Kit |
|
K747-100 |
Biovision |
each |
EUR 392.4 |
) Neutrophil Elastase Activity Assay kit (Fluorometric) |
|
K383-100 |
Biovision |
each |
EUR 502.8 |
Myeloperoxidase (MPO) Colorimetric Activity Assay Kit |
|
K2168-100 |
ApexBio |
100 assays |
EUR 703.2 |
Myeloperoxidase (MPO) Fluorometric Activity Assay Kit |
|
K2169-100 |
ApexBio |
100 assays |
EUR 686.4 |
) Adenosine Deaminase Activity Assay Kit (Colorimetric) |
|
K321-100 |
Biovision |
each |
EUR 502.8 |
) Adenosine Deaminase Activity Assay Kit (Fluorometric) |
|
K328-100 |
Biovision |
each |
EUR 548.4 |
) Caspase-3 Activity Assay Kit II (Fluorometric) |
|
K533-100 |
Biovision |
each |
EUR 614.4 |
 96-well Checkpoint Kinase Activity Assay Kit |
|
STA-414 |
Cell Biolabs |
96 assays |
EUR 908.4 |
|
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors. |
96-well Checkpoint Kinase Activity Assay Kit |
|
STA-414-5 |
Cell Biolabs |
5 x 96 assays |
EUR 3672 |
|
Description: Our 96-well Checkpoint Kinase Activity Assay Kit provides a non-isotopic, sensitive and specific method to monitor checkpoint kinase activity using its physiological substrate; it can also be used in screening checkpoint kinase inhibitors. |
 MMP-3 Activity Fluorometric Assay Kit |
|
K783-100 |
Biovision |
each |
EUR 614.4 |
 PLTP Activity Fluorometric Assay Kit II |
|
K593-100 |
Biovision |
each |
EUR 705.6 |
 CETP Activity Fluorometric Assay Kit II |
|
K595-100 |
Biovision |
each |
EUR 770.4 |
) PicoProbe? Hexokinase Activity Assay Kit (Fluorometric) |
|
K769-100 |
Biovision |
each |
EUR 764.4 |
) HRV 3C Protease Activity Assay Kit (Colorimetric) |
|
K214-100 |
Biovision |
each |
EUR 679.2 |
 Ceruloplasmin Activity Colorimetric Assay Kit |
|
K669-100 |
Biovision |
each |
EUR 660 |
 Neuraminidase Activity Fluorometric Assay Kit |
|
K732-100 |
Biovision |
each |
EUR 627.6 |
Neuraminidase Activity Fluorometric Assay Kit |
|
K2230-100 |
ApexBio |
100 assays |
EUR 718.8 |
 HIF-1 Alpha DNA Binding Activity Assay Kit |
|
CBA-282 |
Cell Biolabs |
96 assays |
EUR 762 |
|
Description: Cell Biolabs? HIF-1 Alpha DNA Binding Activity Assay Kit is an immunoassay developed for rapid detection of activated HIF-1 in any protein sample. Active HIF-1 complex is captured on a double stranded oligonucleotide containing an HRE that is attached to the well. HIF-1 Alpha is then detected with an anti-HIF-1 Alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays, and can detect HIF-1 Alpha from human, mouse, or rat. The HIF-1 DNA Binding Activity Assay takes only 4.5 hours to complete compared to a standard 3 day electromobility shift (EMSA) method. |
) HIV-1 Protease Activity Assay Kit (Fluorometric) |
|
K825-100 |
Biovision |
each |
EUR 679.2 |
) HIV-2 Protease Activity Assay Kit (Fluorometric) |
|
K845-100 |
Biovision |
each |
EUR 705.6 |
 Human Thrombin Chromogenic AssaySense Activity Assay Kit |
|
CT4010 |
AssayPro |
96 Well Plate |
EUR 702 |
 Rat Renin Activity Fluorometric Assay Kit |
|
K806-100 |
Biovision |
each |
EUR 777.6 |
 Lipase Activity Colorimetric Assay Kit II |
|
K723-100 |
Biovision |
each |
EUR 646.8 |
 EpiQuik HAT Activity/Inhibition Assay Kit |
|
P-4003 |
EpiGentek |
-
EUR 771.66
-
EUR 293.70
-
EUR 512.60
|
- 96 Assays
- 48 Assays
- 96 Assays
|
 Factor Xa Activity Fluorometric Assay Kit |
|
K361-100 |
Biovision |
each |
EUR 744 |
Faulty In Cullin Neddylation 1 Area Containing 1 oncogene expression in prostate cancerous tissues was considerably related to excessive Gleason rating (p<0.001), metastasis (p<0.05) and pathological stage (p<0.001). The oncogene was discovered to be an impartial prognostic issue for disease-free survival of prostate most cancers sufferers (p=0.0108). In vitro evaluation confirmed the tumour promotive position of the oncogene by means of cell proliferation, invasion and migration assays. Its expression was carefully correlated with aggressive development and poor prognosis in prostate most cancers sufferers (p<0.05). Vimentin and epithelial cadherin had been affected by the oncogene.
